Research
With no single known cause, no definitive diagnostic test and no cure, ALS remains a tragically confounding neurodegenerative disease. Its progression varies dramatically from patient to patient, leaving clinicians and…
A neurosurgeon and his team from the University of California (UC) Davis Health have won The Herbert Pardes Clinical Research Excellence Award — given by the nonprofit Clinical Research Forum — for…
The first patient has been dosed in a Phase 1 clinical study testing AMX0114, an experimental therapy being developed by Almylyx Pharmaceuticals for amyotrophic lateral sclerosis (ALS). The treatment targets calpain-2, a protein believed to…
A single dose of Insmed’s investigational gene therapy INS1202 preserved motor function and prolonged survival in a mouse model of amyotrophic lateral sclerosis (ALS) associated with SOD1 gene mutations. The therapy was also found to…
The ALS Network, in partnership with ALS United, proudly announces that letters of intent for ALS research funding will be accepted April 15 – May 15, 2025. “We are honored…
JERSEY CITY, N.J. March 12, 2025 – Mitsubishi Tanabe Pharma America, Inc. (MTPA) today announced the presentation of eleven abstracts covering research in amyotrophic lateral sclerosis (ALS) at the 2025…
Dr. Karen DaSilva has been practicing medicine since 2006. She worked at the Sansum Clinic since 2011, and then transferred to The Queen’s Health Systems. Dr. DaSilva received her medical…
Fat molecules called polyunsaturated fatty acids, or PUFAs, can help lessen nerve damage in amyotrophic lateral sclerosis (ALS), according to a study of fruit flies and cell models. Previous studies…
Recently studies have shown ALS in the United States to be more commonly diagnosed in White males over 60 years of age. Previous epidemiologic studies addressing racial variation in ALS…
ALS affects individuals across all backgrounds, yet representation in ALS research has long been skewed. Data reveals that approximately 95% of participants in previous ALS clinical trial studies were Caucasian,…